Piperacillin–tazobactam as alternative to carbapenems for ICU patients
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Piperacillin–tazobactam as alternative to carbapenems for ICU patients
Several studies suggest that alternatives to carbapenems, and particulary beta-lactam/beta-lactamase inhibitor combinations, can be used for therapy of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE)-related infections in non-ICU patients. Little is known concerning ICU patients in whom achieving the desired plasmatic pharmacokinetic/pharmacodynamic (PK/PD) target may be...
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n engl j med 355;25 www.nejm.org december 21, 2006 2693 Gaynes R, Edwards JR. Overview of nosocomial infections caused by gram-negative bacilli. Clin Infect Dis 2005;41:84854. Kollef MH, Shorr A, Tabak YP, Gupta V, Liu LZ, Johannes RS. Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia. Chest 2005;128:3854-62. [Erratum, ...
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ژورنال
عنوان ژورنال: Annals of Intensive Care
سال: 2017
ISSN: 2110-5820
DOI: 10.1186/s13613-017-0334-x